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Delivering the vaccination strategy

1 October 2025

Information and resources for healthcare leaders on the barriers, success factors and enablers for vaccination programme delivery.

By April 2027, responsibility for the commissioning of vaccination services and suitable elements of screening pathways will be transferred to integrated care boards (ICBs), giving ICBs responsibility for a wider range of prevention services for their populations. This is a core component of the NHS Vaccination Strategy, which aims to reduce morbidity and mortality from vaccine-preventable diseases by increasing vaccination uptake and coverage, particularly in underserved populations.

To support ongoing national work on commissioning, we have listened to our members to understand the critical success factors for the effective provision and delivery of vaccination programmes and to gather case studies of programme delivery. This project has been supported by the Association of the British Pharmaceutical Industry (ABPI) and provides examples and insights from a range of vaccination programmes. 

Our work with health leaders has highlighted that a future vaccination offer should:

  • enable local flexibility
  • facilitate strong local leadership for vaccination
  • offer flexibility to design services that are culturally sensitive and that meet the needs of local populations, with expert public health input.

For further information or if you have resources you would like to see included on the hub, please contact the NHS Confederation Primary Care Network at: PrimaryCare@nhsconfed.org

About the project

This project has been supported by The Association of the British Pharmaceutical Industry (ABPI), whose membership includes companies which research, manufacture and supply vaccines for the UK’s national immunisation programmes

The insights gathered throughout this project have come from conversations with NHS Confederation members across the healthcare system and a roundtable with primary care and system leaders, which took place in June 2025.

Vaccination programme delivery in action

Case studies and examples of successful vaccination programme delivery across England.

Case studies and examples

Derbyshire Team Up Pathway

The PCN-led Team Up service is delivering vaccinations to the frail population of Derby and Derbyshire.

The RSV vaccine community pharmacy Pathfinder programme in the East of England

Selected community pharmacies in the East of England have successfully contributed to the RSV vaccination CP pathfinder programme since October 2024.

SECAmb: supporting flu vaccination uptake among frontline healthcare workers

South East Coast Ambulance Service NHS Foundation Trust (SECAmb) achieved 73.7 per cent uptake of the flu vaccination among frontline healthcare staff.

Swan Practice: proactive interventions for asylum seekers

Increasing capacity to support registration and check vaccination records of asylum seekers.

Cambridgeshire and Peterborough ICS: Access and Inequalities Nurse Project

Improving vaccination uptake through its centrally-funded Access and Inequalities Nurse Project.

NHS Birmingham and Solihull: addressing MMR vaccine hesitancy

Overcoming vaccine hesitancy among ethnic and religious groups.

Peterborough Locality: Improving MMR vaccination uptake in response to an outbreak in a neighbouring system

Improving MMR vaccination uptake.

Delivering at-scale vaccinations through a GP federation

Since 2020, the Alliance for Better Care GP federation has supported its member practices across 24 PCNs in Surrey and Sussex to deliver vaccinations.

Generating demand for vaccinations in East Staffordshire

East Staffordshire Primary Care Network reduced the duration of its vaccine hub, which led to increased patient demand.

Alliance for Better Care: learnings from proactive outreach

Improving vaccination access, experience and outcomes for underserved groups across Surrey and Sussex.

Using a bus to deliver vaccines to hard-to-reach groups

Kent and Medway ICS's expanded use of a ‘vaccine bus’ to also offer mini health checks has proved popular.

Addressing vaccine hesitancy concerns in Leicester

Six GP practices in Leicester worked with partners on a personalised approach to vaccine hesitancy concerns, which led to increased vaccine uptake.

Addressing vaccine hesitancy in different ethnic communities

In 2020, COVID-19 vaccination data for Cheshire and Merseyside showed a lot of vaccine hesitancy, especially among ethnic minority groups.

Critical success factors for vaccination programme delivery

Drawing on successful examples from healthcare leaders across England, we have identified key success factors that underpin effective vaccination programme delivery.

Improve access & stimulate demand; Facilitate uptake in underserved areas; Join up vaccs &prevention

View the online version.

Transfer of vaccination commissioning responsibility

Discover what you need to know as responsibility transfers to integrated care boards following legislation in April 2027.

Access the briefing

Resources and guidance

Further information on vaccination policy, vaccination uptake data and vaccination programme delivery.

National guidance and policy
Communications, campaign and education resources
Vaccination uptake and coverage data across all programmes
Reports and commentary